Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04711.1SMART: ATPase, AAA+ type, core; KEGG: hvo:HVO_0341 hypothetical protein. (360 aa)    
Predicted Functional Partners:
AEN04712.1
KEGG: hvo:HVO_0340 hypothetical protein.
       0.778
rad50
DNA double-strand break repair rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily.
 
   
 0.678
AEN07125.1
PFAM: Protein of unknown function DUF87; KEGG: hma:rrnAC0538 hypothetical protein.
  
     0.665
AEN04551.1
PFAM: Type II secretion system F domain; KEGG: hbo:Hbor_24640 hypothetical protein.
 
     0.659
AEN04539.1
PFAM: Protein of unknown function DUF357; KEGG: hla:Hlac_0959 protein of unknown function DUF357.
 
     0.538
AEN06019.1
PFAM: Type II secretion system F domain; KEGG: hbo:Hbor_20820 archaeal flagella assembly protein J.
 
     0.516
AEN04710.1
KEGG: hut:Huta_2746 hypothetical protein.
       0.473
AEN04709.1
PFAM: Aminoglycoside phosphotransferase; KEGG: hut:Huta_2466 aminoglycoside phosphotransferase.
       0.470
crcB
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
  
    0.462
crcB-2
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
  
    0.452
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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