Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN04716.1PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hvo:HVO_0756 phosphoesterase RecJ domain-containing protein. (385 aa)    
Predicted Functional Partners:
AEN04545.1
PFAM: NAD-dependent epimerase/dehydratase; KEGG: hmu:Hmuk_3050 NAD-dependent epimerase/dehydratase.
   
   0.709
AEN04717.1
PFAM: Aldo/keto reductase; KEGG: hbo:Hbor_24560 oxidoreductase, aryl-alcohol dehydrogenase like protein.
       0.708
pcm
Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.544
AEN04546.1
KEGG: hwa:HQ1184A hypothetical protein.
       0.527
AEN04714.1
KEGG: hvo:HVO_0475 hypothetical protein.
       0.448
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
   
 0.432
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
       0.432
AEN05311.1
PFAM: Protein of unknown function DUF790, endonuclease-like; KEGG: hvo:HVO_1596 hypothetical protein.
 
     0.429
AEN07055.1
TIGRFAM: DNA-binding protein Tfx, archaea; KEGG: hbo:Hbor_28760 DNA-binding protein, tfx family.
  
     0.425
AEN06816.1
PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; KEGG: hbo:Hbor_25300 condensin subunit scpa.
 
    0.419
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.