STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN04724.1PFAM: NUDIX hydrolase domain; KEGG: hbo:Hbor_26590 ADP-ribose pyrophosphatase. (141 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.910
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
     
 0.795
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.622
AEN04677.1
PFAM: Ribonuclease II/R; KEGG: hla:Hlac_0359 ribonuclease II.
  
 0.469
AEN05512.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: hma:rrnAC3197 trehalose/maltose binding protein.
  
     0.436
AEN07300.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hbo:Hbor_26610 2-keto-3-deoxygluconate kinase.
     
 0.431
AEN05606.1
Hypothetical protein; KEGG: tsc:TSC_c15780 N-6 DNA methylase family.
 
   
 0.417
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.