Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04728.1PFAM: Tetratricopeptide TPR-1; KEGG: hbo:Hbor_01120 tetratricopeptide hypothetical protein. (246 aa)    
Predicted Functional Partners:
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
  
 0.974
dnaK
Chaperone protein dnaK; Acts as a chaperone.
 
 0.969
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
 0.962
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.959
AEN05667.1
KEGG: nph:NP3056A peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type.
  
 0.920
AEN06012.1
Heat shock protein DnaJ domain protein; KEGG: hbo:Hbor_22210 DnaJ-class molecular chaperone with C-terminal zn finger domain; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal.
 
 0.918
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 0.914
AEN04840.1
PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Glucose-methanol-choline oxidoreductase, C-terminal; KEGG: hsl:OE2509R oxidoreductase-like protein.
    
 0.910
AEN04729.1
PFAM: Protein of unknown function DUF424; KEGG: hbo:Hbor_01130 hypothetical protein.
       0.907
AEN04710.1
KEGG: hut:Huta_2746 hypothetical protein.
 
 
 0.896
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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