STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN04741.1PFAM: Major facilitator superfamily MFS-1; KEGG: hla:Hlac_1455 major facilitator superfamily MFS_1. (402 aa)    
Predicted Functional Partners:
AEN06167.1
KEGG: hvo:HVO_1134 hypothetical protein.
  
     0.720
AEN05492.1
PFAM: Protein of unknown function DUF87; KEGG: hbo:Hbor_07980 ATPase.
 
     0.656
AEN07001.1
Transcriptional regulator, XRE family; SMART: Helix-turn-helix type 3; KEGG: hvo:HVO_2718 hypothetical protein.
  
     0.644
AEN07141.1
Thioredoxin; KEGG: hbo:Hbor_15610 thioredoxin.
  
 
 
 0.630
AEN04740.1
KEGG: hvo:HVO_0758 hypothetical protein.
       0.569
AEN05686.1
KEGG: hla:Hlac_2039 hypothetical protein.
  
     0.560
AEN05976.1
KEGG: hbo:Hbor_18040 hypothetical protein.
  
     0.557
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.
 
     0.547
AEN05669.1
KEGG: hmu:Hmuk_1377 hypothetical protein.
  
     0.547
aroB
3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.
       0.521
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.