Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04744.1PFAM: Phosphate transporter; KEGG: hje:HacjB3_00405 sodium-dependent phosphate transporter. (404 aa)    
Predicted Functional Partners:
AEN04743.1
KEGG: hvo:HVO_0247 hypothetical protein.
       0.773
AEN05704.1
PFAM: Phosphate transporter; KEGG: hmu:Hmuk_3255 phosphate transporter.
  
     0.744
AEN04745.1
Hypothetical protein.
       0.501
AEN05387.1
PFAM: Cytochrome c oxidase, subunit I; Cytochrome c oxidase, subunit III; KEGG: hbo:Hbor_15740 heme/copper-type cytochrome/quinol oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.488
aroB
3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.
       0.486
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: hla:Hlac_2699 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
     
 0.442
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.426
AEN04741.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hla:Hlac_1455 major facilitator superfamily MFS_1.
 
     0.425
AEN04561.1
PFAM: Phosphoadenosine phosphosulphate reductase; KEGG: hvo:HVO_1079 sulfate adenylyltransferase small subunit.
 
  
 0.418
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
     
 0.414
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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