Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04748.1KEGG: nmg:Nmag_3921 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR. (242 aa)    
Predicted Functional Partners:
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
  
 
 0.830
AEN04747.1
PFAM: Oxidoreductase, molybdopterin binding; KEGG: hbo:Hbor_25440 sulfite oxidase-like oxidoreductase.
   
   0.564
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
  
 0.546
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
   
 0.531
AEN04728.1
PFAM: Tetratricopeptide TPR-1; KEGG: hbo:Hbor_01120 tetratricopeptide hypothetical protein.
  
 0.503
AEN05667.1
KEGG: nph:NP3056A peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type.
 
 0.488
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.480
AEN06962.1
PFAM: Histone deacetylase superfamily; KEGG: hvo:HVO_0522 HdaI-type histone deacetylase.
   
 0.476
AEN05447.1
PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; Biotin/lipoyl attachment; KEGG: hbo:Hbor_11200 acetyl/propionyl-CoA carboxylase, alpha subunit.
 
 
 0.463
AEN06800.1
TIGRFAM: Glutamine synthetase type I; KEGG: hbo:Hbor_29510 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
  
 0.457
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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