Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04827.1Transcriptional activator, TenA family; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C; KEGG: hla:Hlac_2986 transcriptional activator, TenA family. (202 aa)    
Predicted Functional Partners:
AEN04825.1
TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: hla:Hlac_2988 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase.
 
 
 0.994
AEN04826.1
KEGG: hla:Hlac_2987 transcriptional activator, TenA family; PFAM: TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C.
 
  
 
0.989
AEN06849.1
ABC-type transporter, integral membrane subunit; PFAM: Cobalt transport protein; KEGG: nmg:Nmag_0888 cobalt transport protein.
  
  
 0.884
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
     
 0.873
AEN05807.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.863
engB
GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation.
       0.588
AEN06528.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: hla:Hlac_0421 UBA/ThiF-type NAD/FAD binding protein.
  
  
 0.587
AEN06628.1
PFAM: ThiamineS; KEGG: hvo:HVO_0202 hypothetical protein.
  
    0.538
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
     
 0.525
AEN05772.1
ATP/cobalamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal; KEGG: hbo:Hbor_08280 ATP:cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type.
     
 0.517
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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