Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
AEN04843.1KEGG: hma:rrnAC1892 DsbA-like thioredoxin domain-containing protein. (221 aa)    
Predicted Functional Partners:
AEN04842.1
KEGG: hma:rrnAC1891 hypothetical protein.
       0.907
AEN04844.1
Fumarylacetoacetate (FAA) hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; KEGG: nmg:Nmag_0827 fumarylacetoacetate (FAA) hydrolase.
       0.592
AEN04841.1
KEGG: hut:Huta_1872 hypothetical protein.
       0.545
AEN04838.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: hmu:Hmuk_2277 extracellular solute-binding protein family 1.
 
  
 0.508
AEN04840.1
PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Glucose-methanol-choline oxidoreductase, C-terminal; KEGG: hsl:OE2509R oxidoreductase-like protein.
       0.422
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 
 0.418
AEN04669.1
KEGG: hbo:Hbor_27990 excinuclease ABC subunit A; TIGRFAM: Excinuclease ABC, A subunit; PFAM: ABC transporter-like.
 
   
 0.416
AEN04835.1
KEGG: hmu:Hmuk_2274 hypothetical protein.
 
     0.416
AEN04839.1
KEGG: hma:rrnAC0905 hypothetical protein.
 
     0.410
AEN05964.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin domain; KEGG: hvo:HVO_2786 thioredoxin.
 
 
 0.409
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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