Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN04853.1PFAM: UspA; KEGG: htu:Htur_2792 UspA domain protein. (146 aa)    
Predicted Functional Partners:
AEN04852.1
Peptidase M50; KEGG: hmu:Hmuk_0406 peptidase M50; PFAM: Peptidase M50; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; Belongs to the peptidase M50B family.
  
    0.656
AEN06619.1
PFAM: UspA; KEGG: hma:rrnAC0402 universal stress protein.
  
     0.601
AEN04854.1
KEGG: nph:NP3904A hypothetical protein.
       0.559
AEN06991.1
PFAM: UspA; KEGG: hla:Hlac_0570 UspA domain protein.
 
     0.533
AEN06718.1
CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; KEGG: hla:Hlac_3545 CBS domain containing protein.
 
    0.448
AEN05492.1
PFAM: Protein of unknown function DUF87; KEGG: hbo:Hbor_07980 ATPase.
       0.445
AEN04851.1
KEGG: htu:Htur_4468 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE.
       0.439
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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