Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN04860.1PFAM: Kinetochore-Ndc80 complex, subunit Spc25; KEGG: nph:NP4262A rad50 ATPase. (646 aa)    
Predicted Functional Partners:
AEN04859.1
KEGG: hbo:Hbor_36760 hypothetical protein.
     
 0.767
AEN06982.1
PFAM: Abortive infection protein; KEGG: hje:HacjB3_14285 abortive infection protein.
  
     0.683
AEN04661.1
LVIVD repeat-containing protein; PFAM: LVIVD; KEGG: hvo:HVO_0405 NifU-like domain-containing protein.
  
     0.621
AEN05694.1
KEGG: hma:pNG6077 hypothetical protein.
  
     0.577
AEN04562.1
PFAM: Bacterio-opsin activator, HTH; KEGG: hma:rrnAC2472 bacterio-opsin activator.
  
     0.572
AEN06956.1
PFAM: Bacterio-opsin activator, HTH; KEGG: htu:Htur_0497 bacterio-opsin activator HTH domain protein.
  
     0.569
AEN06696.1
KEGG: hwa:HQ3226A hypothetical protein.
  
     0.551
AEN04861.1
KEGG: htu:Htur_2872 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR, C-terminal; Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal.
 
     0.544
AEN05258.1
PFAM: Bacterio-opsin activator, HTH; KEGG: hbo:Hbor_34330 predicted DNA binding protein.
  
     0.541
AEN06374.1
PFAM: NHL repeat; KEGG: hvo:HVO_0336 hypothetical protein.
  
     0.530
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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