Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN04940.1KEGG: htu:Htur_0070 phosphoserine phosphatase SerB; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like; PFAM: Haloacid dehalogenase-like hydrolase. (211 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.949
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 
 0.932
AEN05352.1
Serine--pyruvate transaminase; KEGG: htu:Htur_1862 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase.
   
 0.930
AEN06295.1
KEGG: hbo:Hbor_39870 L-threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT.
    
 0.913
AEN06807.1
KEGG: hvo:HVO_0464 threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT.
    
 0.913
AEN06953.1
Threonine ammonia-lyase; KEGG: hmu:Hmuk_3238 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
    
 0.913
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.911
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.873
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.842
hisB
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: hla:Hlac_2701 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
  
  
 0.831
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.