Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04941.1TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: hbo:Hbor_02900 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. (527 aa)    
Predicted Functional Partners:
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family.
  
 
 0.909
AEN04940.1
KEGG: htu:Htur_0070 phosphoserine phosphatase SerB; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like; PFAM: Haloacid dehalogenase-like hydrolase.
  
 
 0.671
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.628
AEN06204.1
KEGG: cyt:cce_0338 acylneuraminate cytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase.
      0.595
udk
TIGRFAM: Uridine kinase; HAMAP: Uridine kinase; KEGG: hla:Hlac_1557 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase.
   
  0.534
AEN04691.1
KEGG: hje:HacjB3_15185 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal.
 
 
 0.493
AEN04939.1
Alanine--glyoxylate transaminase; KEGG: hsl:OE4391F aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase); PFAM: Aminotransferase, class V/Cysteine desulfurase.
 
  
 0.483
AEN06962.1
PFAM: Histone deacetylase superfamily; KEGG: hvo:HVO_0522 HdaI-type histone deacetylase.
 
 
 0.471
AEN06198.1
N-acetylneuraminate synthase; KEGG: bja:blr5971 polysaccharide biosynthesis related protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; Xylose isomerase, TIM barrel domain.
   
   0.456
AEN05162.1
KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
 
  
 0.447
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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