Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05001.1Multi-sensor signal transduction histidine kinase; KEGG: hma:rrnAC2789 HTR-like protein; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like. (564 aa)    
Predicted Functional Partners:
AEN06047.1
TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; KEGG: hsl:OE6145R putative signal-transducing histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
 
   
 0.687
AEN06325.1
TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS fold-4; KEGG: hbo:Hbor_10850 fused histidine kinase with gaf domain/response regulator receiver; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS.
 
   
 0.682
AEN05002.1
KEGG: htu:Htur_3209 putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.618
AEN07008.1
TIGRFAM: Phosphoribosyl pyrophosphokinase; KEGG: hmu:Hmuk_0911 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.588
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
   
 0.584
AEN06482.1
Pyruvate dehydrogenase (acetyl-transferring); KEGG: hla:Hlac_0140 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal.
    
 0.581
AEN05000.1
KEGG: hmu:Hmuk_1398 hypothetical protein.
       0.541
AEN05212.1
KEGG: hla:Hlac_1208 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; HalX; SMART: Signal transduction response regulator, receiver region.
 
 
 
 0.514
AEN04510.1
PFAM: Peptidase S1/S6, chymotrypsin/Hap; KEGG: hma:rrnAC0296 serine protease HtrA.
 
  
 0.509
AEN06481.1
TIGRFAM: Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; KEGG: hla:Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase, E1 component.
   
 0.488
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.