Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05035.1PFAM: Cation transporter; KEGG: hvo:HVO_1057 trk potassium uptake system protein TrkH. (535 aa)    
Predicted Functional Partners:
AEN06384.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_05150 sodium/proton antiporter, cpa1 family.
 
 
 0.956
AEN05034.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_22420 k+ transporter, NAD-binding component.
 
   
 0.933
AEN05653.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_06490 k+ transporter, NAD-binding component.
 
 
 0.895
AEN05036.1
Transcriptional regulator, HxlR family; PFAM: Helix-turn-helix, HxlR type; KEGG: hbo:Hbor_34250 predicted transcriptional regulator.
       0.558
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
     
 0.496
AEN06058.1
NADH dehydrogenase (quinone); KEGG: hbo:Hbor_22540 NADH:ubiquinone oxidoreductase subunit 5 (chain l)/multisubunit na+/h+ antiporter, mnha subunit; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal.
     
 0.492
AEN05033.1
Cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; KEGG: hbo:Hbor_22440 polyketide cyclase / dehydrase and lipid transport.
       0.467
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.