Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05047.1KEGG: hbo:Hbor_25200 hypothetical protein. (315 aa)    
Predicted Functional Partners:
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
 
     0.952
rps27e
KEGG: hvo:HVO_0700 30S ribosomal protein S27.eR; HAMAP: 30S ribosomal protein S27e; PFAM: Ribosomal protein S27e.
 
     0.945
AEN05045.1
PFAM: Eukaryotic translation initiation factor 2, alpha subunit; Ribosomal protein S1, RNA binding domain; KEGG: hbo:Hbor_25180 translation initiation factor 2 subunit alpha (aeif-2a).
 
    0.931
nop10
Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.871
polC
DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
  
     0.718
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
  
     0.697
AEN04737.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hbo:Hbor_01460 single-stranded DNA-specific exonuclease.
  
     0.695
AEN05910.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: hma:rrnAC3263 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.685
rpl31e
KEGG: hmu:Hmuk_1233 ribosomal protein L31e; HAMAP: 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
     0.677
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
     0.675
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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