Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05076.1KEGG: hmu:Hmuk_2780 hypothetical protein. (260 aa)    
Predicted Functional Partners:
AEN05077.1
PFAM: Peptidase M24, structural domain; Creatinase; KEGG: hvo:HVO_0997 Xaa-Pro aminopeptidase M24 family protein; Belongs to the peptidase M24B family.
       0.551
AEN05075.1
Putative signal transduction protein with CBS domains; KEGG: hvo:HVO_0991 CBS/ParB domain-containing protein; PFAM: Cystathionine beta-synthase, core; ParB-like nuclease; SMART: Cystathionine beta-synthase, core; ParB-like nuclease.
       0.550
AEN05074.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hla:Hlac_0324 phosphoesterase RecJ domain protein.
       0.464
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (8%) [HD]