Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05133.1PFAM: GHMP kinase; GHMP kinase, C-terminal; KEGG: hla:Hlac_1434 GHMP kinase. (332 aa)    
Predicted Functional Partners:
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
 
 0.996
AEN05278.1
Aspartate/glutamate/uridylate kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
  
  
 0.975
AEN07279.1
KEGG: hbo:Hbor_08530 hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Hydroxymethylglutaryl-coenzyme A synthase C-terminal.
 
 
 0.933
AEN07149.1
PFAM: Protein of unknown function DUF35; KEGG: nph:NP2608A hydroxymethylglutaryl-CoA synthase 1.
 
 
 0.807
idi
Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.775
AEN06468.1
TIGRFAM: Hydroxymethylglutaryl-CoA reductase, class I, catalytic; KEGG: hvo:HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH); PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic; Belongs to the HMG-CoA reductase family.
 
  
 0.741
AEN05132.1
PFAM: Protein of unknown function DUF21; KEGG: hma:rrnAC2730 hypothetical protein.
       0.548
AEN06381.1
KEGG: hla:Hlac_1850 acetyl-CoA acetyltransferase; TIGRFAM: Thiolase.
 
  
 0.509
AEN07150.1
KEGG: hvo:HVO_A0522 acetyl-CoA C-acyltransferase; PFAM: Beta-ketoacyl synthase, N-terminal.
 
  
 0.498
AEN04921.1
Propanoyl-CoA C-acyltransferase; KEGG: hbo:Hbor_22070 acetyl-CoA acetyltransferase.
 
  
 0.497
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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