Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05136.1PFAM: Molybdopterin binding; KEGG: hvo:HVO_1177 CinA N-terminal domain-containing protein. (230 aa)    
Predicted Functional Partners:
AEN04556.1
CinA domain protein; KEGG: hbo:Hbor_24930 competence/damage-inducible protein CinA-like protein; TIGRFAM: CinA, C-terminal; PFAM: CinA, C-terminal.
   
 0.949
AEN06176.1
Lipoprotein; KEGG: hvo:HVO_1176 lipoprotein.
       0.682
AEN05137.1
PFAM: Methyltransferase type 11; KEGG: hla:Hlac_1030 methyltransferase type 11.
       0.613
AEN05138.1
PFAM: Type II secretion system F domain; KEGG: hvo:HVO_1033 type IV pilus biogenesis complex membrane subunit.
       0.613
AEN05139.1
KEGG: hla:Hlac_1032 type II secretion system protein E; manually curated; PFAM: Type II secretion system protein E.
       0.613
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; KEGG: htu:Htur_0284 glyceraldehyde-3-phosphate dehydrogenase, type II.
 
     0.477
AEN05140.1
KEGG: hbo:Hbor_22160 hypothetical protein.
       0.460
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...]
       0.456
AEN06175.1
PFAM: Uncharacterised conserved protein UCP019322; KEGG: hbo:Hbor_20660 hypothetical protein.
       0.456
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
       0.421
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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