Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEN05137.1PFAM: Methyltransferase type 11; KEGG: hla:Hlac_1030 methyltransferase type 11. (211 aa)    
Predicted Functional Partners:
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
   
 0.959
AEN05139.1
KEGG: hla:Hlac_1032 type II secretion system protein E; manually curated; PFAM: Type II secretion system protein E.
   
   0.912
AEN05138.1
PFAM: Type II secretion system F domain; KEGG: hvo:HVO_1033 type IV pilus biogenesis complex membrane subunit.
       0.907
AEN05141.1
KEGG: hbo:Hbor_22170 hypothetical protein.
       0.712
AEN06596.1
PFAM: Putative RNA methylase; KEGG: htu:Htur_0132 putative RNA methylase.
   
 0.680
AEN05140.1
KEGG: hbo:Hbor_22160 hypothetical protein.
       0.660
AEN05136.1
PFAM: Molybdopterin binding; KEGG: hvo:HVO_1177 CinA N-terminal domain-containing protein.
       0.613
AEN06115.1
Ribosomal protein S5; KEGG: hla:Hlac_2429 30S ribosomal protein S5P; TIGRFAM: Ribosomal protein S5, eukaryotic/archaeal; PFAM: Ribosomal protein S5, N-terminal; Ribosomal protein S5, C-terminal; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.591
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 0.557
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
  
   
 0.552
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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