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ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (347 aa)    
Predicted Functional Partners:
AEN05162.1
KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
 
 
 0.999
AEN05163.1
TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: hma:rrnAC0330 acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region.
 
 
 0.998
ilvD
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: hvo:HVO_2646 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.993
AEN05023.1
Acetolactate synthase; KEGG: nmg:Nmag_2521 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Belongs to the TPP enzyme family.
 
 
 0.990
AEN05159.1
KEGG: nph:NP2194A isopropylmalate isomerase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit region; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha.
  
  
 0.988
AEN05158.1
KEGG: nph:NP2192A 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit region; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel.
  
  
 0.986
AEN05845.1
KEGG: hje:HacjB3_10520 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
  
 0.959
AEN06491.1
KEGG: hje:HacjB3_07995 acetolactate synthase; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
  
  0.923
AEN04961.1
KEGG: hvo:HVO_A0489 homocitrate synthase; PFAM: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
 0.860
AEN05160.1
KEGG: nph:NP2196A hypothetical protein.
       0.820
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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