Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05188.1PFAM: Inositol monophosphatase; KEGG: hut:Huta_1341 inositol monophosphatase. (265 aa)    
Predicted Functional Partners:
AEN05567.1
PFAM: Inositol monophosphatase; KEGG: hmu:Hmuk_0111 inositol monophosphatase.
  
  
 
0.906
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
   
   0.549
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.494
rpoK
DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
  
   0.492
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: hla:Hlac_2699 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
  
 0.486
hisB
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: hla:Hlac_2701 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
  
  
 0.475
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
   
 
 0.474
AEN05191.1
PFAM: Metallophosphoesterase; KEGG: hbo:Hbor_18990 phosphoesterase.
       0.462
AEN07008.1
TIGRFAM: Phosphoribosyl pyrophosphokinase; KEGG: hmu:Hmuk_0911 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
  
 0.459
AEN05189.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hla:Hlac_0623 replication factor A.
       0.457
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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