Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05191.1PFAM: Metallophosphoesterase; KEGG: hbo:Hbor_18990 phosphoesterase. (255 aa)    
Predicted Functional Partners:
AEN05190.1
KEGG: hla:Hlac_0624 hypothetical protein.
 
   
 0.979
AEN05189.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hla:Hlac_0623 replication factor A.
 
   
 0.976
AEN07111.1
DEAD/H associated domain protein; KEGG: hvo:HVO_1333 ATP-dependent DNA helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
 
    0.769
AEN07059.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hvo:HVO_0292 replication protein A.
 
   
 0.724
AEN07060.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hbo:Hbor_28820 hypothetical protein.
 
   
 0.667
AEN06576.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
  
     0.654
AEN07074.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hbo:Hbor_26830 single-stranded DNA-binding protein.
 
   
 0.636
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
   
 0.631
top6B
DNA topoisomerase (ATP-hydrolyzing); Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
 
     0.625
carS
UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.613
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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