Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN05199.1PFAM: Mechanosensitive ion channel MscS; KEGG: hma:rrnAC1347 mechanosensitive ion channel. (297 aa)    
Predicted Functional Partners:
AEN05200.1
KEGG: hla:Hlac_1188 protein of unknown function UPF0044; manually curated; PFAM: RNA-binding, CRM domain.
       0.889
rnp4
Ribonuclease P protein component 4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
       0.694
AEN05202.1
PFAM: Glycosyl transferase, group 1; KEGG: hsl:OE1906R glycosyltransferase, type 1.
       0.474
AEN04779.1
NMD3 family protein; PFAM: NMD3; KEGG: hbo:Hbor_01210 nmd protein affecting ribosome stability and mRNA decay.
   
    0.472
AEN06384.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_05150 sodium/proton antiporter, cpa1 family.
 
   
 0.438
AEN05203.1
PFAM: Glycosyl transferase, group 1; KEGG: hut:Huta_0088 glycosyl transferase group 1.
       0.410
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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