Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05222.1FG-GAP repeat protein; PFAM: FG-GAP; KEGG: hla:Hlac_1846 FG-GAP repeat protein. (426 aa)    
Predicted Functional Partners:
AEN05223.1
UPF0212 protein; KEGG: hbo:Hbor_16680 hypothetical protein; HAMAP: Uncharacterised protein family UPF0212; PFAM: Uncharacterised protein family UPF0212; Belongs to the UPF0212 family.
       0.773
AEN05694.1
KEGG: hma:pNG6077 hypothetical protein.
  
     0.723
AEN04569.1
Permease; KEGG: hla:Hlac_1131 permease.
 
     0.688
AEN04732.1
KEGG: hbo:Hbor_14080 hypothetical protein.
 
     0.619
AEN06374.1
PFAM: NHL repeat; KEGG: hvo:HVO_0336 hypothetical protein.
  
     0.567
AEN06696.1
KEGG: hwa:HQ3226A hypothetical protein.
  
     0.562
gch3
GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
 
     0.521
AEN06956.1
PFAM: Bacterio-opsin activator, HTH; KEGG: htu:Htur_0497 bacterio-opsin activator HTH domain protein.
  
     0.515
AEN04562.1
PFAM: Bacterio-opsin activator, HTH; KEGG: hma:rrnAC2472 bacterio-opsin activator.
  
     0.503
AEN04835.1
KEGG: hmu:Hmuk_2274 hypothetical protein.
  
     0.427
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.