Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (305 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
  
 0.966
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
 
 
 0.956
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.923
AEN05233.1
TIGRFAM: Isochorismate synthase; KEGG: hje:HacjB3_08360 isochorismate synthase; PFAM: Chorismate binding, C-terminal.
 
   
 0.914
menC
Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
   
 0.837
AEN05387.1
PFAM: Cytochrome c oxidase, subunit I; Cytochrome c oxidase, subunit III; KEGG: hbo:Hbor_15740 heme/copper-type cytochrome/quinol oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.441
AEN05930.1
KEGG: hvo:HVO_2614 uridine phosphorylase; PFAM: Nucleoside phosphorylase.
      
 0.434
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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