Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05236.1PFAM: NUDIX hydrolase domain; KEGG: hut:Huta_0516 NUDIX hydrolase. (170 aa)    
Predicted Functional Partners:
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.622
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
     0.598
menC
Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
       0.546
AEN05239.1
PFAM: Crotonase, core; KEGG: htu:Htur_1610 enoyl-CoA hydratase/isomerase.
  
 0.515
AEN04943.1
KEGG: hbo:Hbor_15640 transposase, IS605 orfB family, central region; TIGRFAM: Transposase, IS605 OrfB, C-terminal; PFAM: Transposase, IS605 OrfB, C-terminal.
  
     0.471
AEN04677.1
PFAM: Ribonuclease II/R; KEGG: hla:Hlac_0359 ribonuclease II.
  
 0.469
AEN05757.1
KEGG: hma:pNG6153 hypothetical protein.
  
     0.468
AEN07058.1
KEGG: hbo:Hbor_15640 transposase, IS605 orfB family, central region; TIGRFAM: Transposase, IS605 OrfB, C-terminal; PFAM: Transposase, IS605 OrfB, C-terminal.
  
     0.467
AEN05460.1
Hypothetical protein; KEGG: pao:Pat9b_5496 ABC transporter substrate-binding protein.
 
     0.446
AEN04640.1
Transposase, IS605 OrfB family; KEGG: nph:NP3036A IS1341-type transposase; TIGRFAM: Transposase, IS605 OrfB, C-terminal; PFAM: Transposase, IS605 OrfB, C-terminal.
  
     0.433
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.