Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05240.1Na+/H+ antiporter NhaC; KEGG: nph:NP4702A sodium/hydrogen, malic/sodium-lactate antiporter; TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like. (492 aa)    
Predicted Functional Partners:
AEN06234.1
PFAM: Sodium/solute symporter; KEGG: hje:HacjB3_04185 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.637
AEN06384.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_05150 sodium/proton antiporter, cpa1 family.
 
   
 0.626
AEN06057.1
PFAM: Na+/H+ antiporter MnhB subunit-related protein; KEGG: hbo:Hbor_22530 multisubunit na+/h+ antiporter, MnhB subunit.
      
 0.605
AEN06058.1
NADH dehydrogenase (quinone); KEGG: hbo:Hbor_22540 NADH:ubiquinone oxidoreductase subunit 5 (chain l)/multisubunit na+/h+ antiporter, mnha subunit; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal.
      
 0.546
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
   
 0.502
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.485
gatD
Glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
    0.430
AEN05087.1
TIGRFAM: NADH-plastoquinone oxidoreductase, chain 5; KEGG: hvo:HVO_0986 NADH dehydrogenase-like complex subunit L; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal.
      
 0.420
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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