STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdkHAMAP: Thymidine kinase, subgroup; KEGG: hvo:HVO_2891 thymidine kinase; PFAM: Thymidine kinase. (195 aa)    
Predicted Functional Partners:
tmk
PFAM: Thymidylate kinase-like; TIGRFAM: Thymidylate kinase; HAMAP: Thymidylate kinase; KEGG: hvo:HVO_2207 thymidylate kinase.
  
 
 0.949
AEN05315.1
KEGG: hmu:Hmuk_2739 cytidine deaminase; TIGRFAM: Cytidine deaminase, homotetrameric; PFAM: CMP/dCMP deaminase, zinc-binding.
    
 0.936
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.930
AEN05864.1
5'-Nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; KEGG: hbo:Hbor_11400 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase.
 
  
  0.923
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.917
AEN05930.1
KEGG: hvo:HVO_2614 uridine phosphorylase; PFAM: Nucleoside phosphorylase.
    
 0.916
AEN06288.1
PFAM: Nucleoside phosphorylase; KEGG: hvo:HVO_1579 uridine phosphorylase.
    
 0.916
AEN05618.1
dUTP diphosphatase; KEGG: hut:Huta_1801 deoxyuridine 5'-triphosphate nucleotidohydrolase.
     
 0.913
AEN05276.1
PFAM: Protein of unknown function DUF2143; KEGG: hmu:Hmuk_2197 hypothetical protein.
       0.759
udk
TIGRFAM: Uridine kinase; HAMAP: Uridine kinase; KEGG: hla:Hlac_1557 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase.
 
  
 0.667
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.