Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05296.1PFAM: Uracil-DNA glycosylase-like; KEGG: hbo:Hbor_12630 uracil-DNA glycosylase. (317 aa)    
Predicted Functional Partners:
AEN06767.1
KEGG: hbo:Hbor_27510 uracil-DNA glycosylase, family 4; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like.
  
  
0.922
AEN06013.1
KEGG: hvo:HVO_1038 uracil DNA glycosylase.
  
  
0.903
AEN05294.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.857
AEN05295.1
KEGG: hvo:HVO_2791 hypothetical protein.
       0.837
AEN05430.1
HhH-GPD family protein; KEGG: hbo:Hbor_14130 a/g-specific DNA-adenine glycosylase; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.
      
 0.477
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
       0.437
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.433
mutS2
DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
     
 0.421
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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