Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05324.1PFAM: Peptidase M48, Ste24p; KEGG: hmu:Hmuk_0373 peptidase M48 Ste24p. (276 aa)    
Predicted Functional Partners:
AEN06182.1
PFAM: GHMP kinase; KEGG: hbo:Hbor_04760 kinase, sugar kinase superfamily.
  
    0.786
AEN05323.1
KEGG: hvo:HVO_A0044 hypothetical protein.
       0.773
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.750
AEN06813.1
PFAM: Auxin efflux carrier; KEGG: hbo:Hbor_25260 permease.
  
  
 0.636
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.614
AEN05954.1
KEGG: hbo:Hbor_02300 malate dehydrogenase (NAD); PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.593
AEN05325.1
PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: hvo:HVO_A0049 magnesium and cobalt efflux protein CorC.
       0.538
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.530
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.521
AEN05775.1
PFAM: Threonyl/alanyl tRNA synthetase, SAD; Alanyl-tRNA synthetase, class IIc, N-terminal; Phosphoesterase, DHHA1; KEGG: hvo:HVO_2717 alanyl-tRNA synthetase.
  
    0.501
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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