Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05368.1PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: hvo:HVO_2662 dioxgenase. (329 aa)    
Predicted Functional Partners:
AEN05184.1
PFAM: Phospholipase/carboxylesterase; KEGG: hla:Hlac_0811 phospholipase/carboxylesterase.
 
     0.677
AEN05091.1
KEGG: hla:Hlac_0708 NADH-quinone oxidoreductase, chain I; TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
  
  
 0.613
AEN05369.1
KEGG: hvo:HVO_1477 endonuclease; PFAM: Staphylococcal nuclease (SNase-like); SMART: Staphylococcal nuclease (SNase-like).
       0.603
AEN05370.1
Hypothetical protein.
       0.601
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.590
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
  
  
 0.548
AEN05641.1
KEGG: hje:HacjB3_08880 succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase, cytochrome b subunit.
  
    0.482
AEN05365.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.470
AEN05923.1
KEGG: hwa:HQ3198A menaquinol--cytochrome-c reductase.
  
  
 0.448
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (26%) [HD]