Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05369.1KEGG: hvo:HVO_1477 endonuclease; PFAM: Staphylococcal nuclease (SNase-like); SMART: Staphylococcal nuclease (SNase-like). (331 aa)    
Predicted Functional Partners:
AEN05370.1
Hypothetical protein.
       0.773
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
 0.730
AEN05368.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: hvo:HVO_2662 dioxgenase.
       0.603
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterised protein family UPF0027; KEGG: hvo:HVO_2712 RNA terminal phosphate cyclase operon orfB-like protein; Belongs to the RtcB family.
     
 0.560
AEN06902.1
KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family.
     
 0.469
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.466
AEN05250.1
TIGRFAM: Protoporphyrinogen oxidase; KEGG: htu:Htur_4343 protoporphyrinogen oxidase; PFAM: Amine oxidase.
 
    0.452
AEN05590.1
TIGRFAM: Protoporphyrinogen oxidase; KEGG: htu:Htur_4343 protoporphyrinogen oxidase; PFAM: Amine oxidase; FAD dependent oxidoreductase.
 
    0.431
AEN07174.1
YYY membrane protein; KEGG: hvo:HVO_0702 hypothetical protein; TIGRFAM: YYY membrane protein; PFAM: YYY membrane protein.
  
    0.422
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
   0.417
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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