| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN04705.1 | AEN05287.1 | Halar_0940 | Halar_1555 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | 0.997 |
| AEN04705.1 | AEN05759.1 | Halar_0940 | Halar_2073 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | KEGG: adn:Alide_4134 hypothetical protein. | 0.825 |
| AEN04705.1 | fen | Halar_0940 | Halar_2605 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.743 |
| AEN04705.1 | rad25 | Halar_0940 | Halar_1672 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Type III restriction protein res subunit; KEGG: hbo:Hbor_14720 DNA/RNA helicase, superfamily II; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | 0.799 |
| AEN04705.1 | rpoH | Halar_0940 | Halar_0942 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.998 |
| AEN04705.1 | rpoN | Halar_0940 | Halar_1551 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.974 |
| AEN04705.1 | rpoP | Halar_0940 | Halar_0996 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.947 |
| AEN04705.1 | tbp | Halar_0940 | Halar_1670 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.788 |
| AEN04705.1 | tfe | Halar_0940 | Halar_2520 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] | 0.914 |
| AEN05287.1 | AEN04705.1 | Halar_1555 | Halar_0940 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.997 |
| AEN05287.1 | AEN05759.1 | Halar_1555 | Halar_2073 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | KEGG: adn:Alide_4134 hypothetical protein. | 0.957 |
| AEN05287.1 | fen | Halar_1555 | Halar_2605 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.778 |
| AEN05287.1 | rad25 | Halar_1555 | Halar_1672 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | Type III restriction protein res subunit; KEGG: hbo:Hbor_14720 DNA/RNA helicase, superfamily II; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | 0.895 |
| AEN05287.1 | rpoH | Halar_1555 | Halar_0942 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.991 |
| AEN05287.1 | rpoN | Halar_1555 | Halar_1551 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.998 |
| AEN05287.1 | rpoP | Halar_1555 | Halar_0996 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.983 |
| AEN05287.1 | tbp | Halar_1555 | Halar_1670 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.862 |
| AEN05287.1 | tfe | Halar_1555 | Halar_2520 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. | Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] | 0.964 |
| AEN05311.1 | rad25 | Halar_1579 | Halar_1672 | PFAM: Protein of unknown function DUF790, endonuclease-like; KEGG: hvo:HVO_1596 hypothetical protein. | Type III restriction protein res subunit; KEGG: hbo:Hbor_14720 DNA/RNA helicase, superfamily II; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | 0.896 |
| AEN05759.1 | AEN04705.1 | Halar_2073 | Halar_0940 | KEGG: adn:Alide_4134 hypothetical protein. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.825 |
