STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN05492.1PFAM: Protein of unknown function DUF87; KEGG: hbo:Hbor_07980 ATPase. (607 aa)    
Predicted Functional Partners:
AEN06167.1
KEGG: hvo:HVO_1134 hypothetical protein.
  
     0.742
rad50
DNA double-strand break repair rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily.
 
   
 0.738
AEN05491.1
KEGG: hla:Hlac_1978 hypothetical protein.
       0.738
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.
 
   
 0.723
AEN05669.1
KEGG: hmu:Hmuk_1377 hypothetical protein.
  
     0.698
AEN05686.1
KEGG: hla:Hlac_2039 hypothetical protein.
  
     0.669
AEN04741.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hla:Hlac_1455 major facilitator superfamily MFS_1.
 
     0.657
AEN07141.1
Thioredoxin; KEGG: hbo:Hbor_15610 thioredoxin.
 
     0.655
AEN05416.1
KEGG: hbo:Hbor_16570 zn-dependent hydrolase of beta-lactamase fold family.
  
     0.604
AEN05215.1
Regulatory protein ArsR; SMART: HTH transcriptional regulator, ArsR; KEGG: hbo:Hbor_16770 transcriptional regulator, ArsR family.
  
     0.596
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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