Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05519.1Glyoxylate reductase; KEGG: nmg:Nmag_0029 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (332 aa)    
Predicted Functional Partners:
AEN05479.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: hla:Hlac_1638 FAD dependent oxidoreductase.
  
    0.545
AEN05467.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: hvo:HVO_1932 2-D-hydroxyacid dehydrogenase.
  
     0.537
udk
TIGRFAM: Uridine kinase; HAMAP: Uridine kinase; KEGG: hla:Hlac_1557 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase.
   
  0.534
rpl6
Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
 
   0.520
AEN06198.1
N-acetylneuraminate synthase; KEGG: bja:blr5971 polysaccharide biosynthesis related protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; Xylose isomerase, TIM barrel domain.
   
   0.456
AEN05845.1
KEGG: hje:HacjB3_10520 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
  
 0.412
AEN05520.1
PFAM: Protein of unknown function DUF1486; KEGG: nmg:Nmag_1448 nuclear transport factor 2.
 
     0.409
AEN04691.1
KEGG: hje:HacjB3_15185 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal.
  
 
 0.403
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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