Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (289 aa)    
Predicted Functional Partners:
AEN06411.1
KEGG: hvo:HVO_1965 Nob1p-like protein.
   
 0.985
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 0.971
AEN06513.1
KH domain protein; KEGG: hbo:Hbor_00890 universal archaeal kh domain protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology.
  
  0.968
AEN06543.1
RIO-like kinase; KEGG: hla:Hlac_0533 protein of unknown function RIO1; PFAM: RIO-like kinase; RIO2 kinase, winged helix, N-terminal; SMART: RIO kinase.
  
 0.966
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 0.960
AEN05545.1
Methylase; KEGG: hbo:Hbor_12120 HemK-related methylase; TIGRFAM: Putative methylase; PFAM: Methyltransferase small.
  
  
 0.932
rps11
Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.930
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.925
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.924
AEN04700.1
PFAM: Ribosomal protein S7; KEGG: hvo:HVO_0354 30S ribosomal protein S7.
 
 0.917
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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