Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05545.1Methylase; KEGG: hbo:Hbor_12120 HemK-related methylase; TIGRFAM: Putative methylase; PFAM: Methyltransferase small. (198 aa)    
Predicted Functional Partners:
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.932
AEN05544.1
PFAM: Mechanosensitive ion channel MscS; KEGG: nph:NP3676A mechanosensitive channel.
       0.907
AEN06596.1
PFAM: Putative RNA methylase; KEGG: htu:Htur_0132 putative RNA methylase.
    
 0.902
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
     
 0.854
AEN05542.1
PFAM: Protein of unknown function DUF655; KEGG: hbo:Hbor_12150 RNA-binding protein.
       0.847
AEN05846.1
Cobalamin-independent synthase MetE domain protein; PFAM: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal; KEGG: hvo:HVO_2743 methionine synthase vitamin-B12 independent.
     
 0.759
AEN05541.1
PFAM: RNA polymerase II, Rpb4; KEGG: hje:HacjB3_08615 RNA polymerase RPB4.
       0.707
rpl21e
KEGG: hbo:Hbor_12170 LSU ribosomal protein l21e; HAMAP: 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
       0.675
AEN05125.1
PFAM: Methyltransferase type 12; KEGG: hbo:Hbor_18530 tRNA(1-methyladenosine) methyltransferase-like methyltransferase.
  
 
 0.659
AEN05669.1
KEGG: hmu:Hmuk_1377 hypothetical protein.
   
 0.648
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (6%) [HD]