Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05588.1PFAM: Mechanosensitive ion channel MscS; KEGG: hvo:HVO_2685 small conductance mechanosensitive ion channel (MscS) family transporter. (347 aa)    
Predicted Functional Partners:
AEN05586.1
PFAM: Protein of unknown function DUF2240; KEGG: hvo:HVO_2372 hypothetical protein.
       0.668
AEN05587.1
KEGG: hvo:HVO_2371 hypothetical protein.
       0.668
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.596
AEN05590.1
TIGRFAM: Protoporphyrinogen oxidase; KEGG: htu:Htur_4343 protoporphyrinogen oxidase; PFAM: Amine oxidase; FAD dependent oxidoreductase.
       0.596
AEN04779.1
NMD3 family protein; PFAM: NMD3; KEGG: hbo:Hbor_01210 nmd protein affecting ribosome stability and mRNA decay.
  
    0.535
AEN07287.1
PFAM: Transcriptional regulator TrmB; KEGG: hje:HacjB3_07145 transcriptional regulator, TrmB.
       0.454
AEN06384.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_05150 sodium/proton antiporter, cpa1 family.
 
   
 0.427
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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