Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05625.1KEGG: hla:Hlac_1268 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1. (145 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.906
AEN06628.1
PFAM: ThiamineS; KEGG: hvo:HVO_0202 hypothetical protein.
  
 
 0.884
AEN05045.1
PFAM: Eukaryotic translation initiation factor 2, alpha subunit; Ribosomal protein S1, RNA binding domain; KEGG: hbo:Hbor_25180 translation initiation factor 2 subunit alpha (aeif-2a).
   
 0.877
AEN06528.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: hla:Hlac_0421 UBA/ThiF-type NAD/FAD binding protein.
 
 0.859
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.836
AEN06328.1
SMART: ATPase, AAA+ type, core; TIGRFAM: 26S proteasome subunit P45; KEGG: hbo:Hbor_05530 proteasome-activating nucleotidase; PFAM: ATPase, AAA-type, core; Belongs to the AAA ATPase family.
  
 0.836
AEN06687.1
KEGG: hla:Hlac_0818 translation initiation factor IF-2 subunit beta; PFAM: Translation initiation factor IF2/IF5; Deoxyribonuclease/rho motif-related TRAM; SMART: Translation initiation factor IF2/IF5.
  
 0.824
AEN07268.1
KEGG: hvo:HVO_0424 ABC transporter ATP-binding protein; PFAM: RNase L inhibitor RLI, possible metal-binding region; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; ABC transporter-like; SMART: ATPase, AAA+ type, core.
   
  0.799
AEN05610.1
TIGRFAM: Archaeal/bacterial translation initiation factor SUI1; HAMAP: Translation factor SUI1-like protein; KEGG: hbo:Hbor_05410 translation initiation factor 1 (eif-1/SUI1); PFAM: Translation initiation factor SUI1; Belongs to the SUI1 family.
   
 0.793
dnaK
Chaperone protein dnaK; Acts as a chaperone.
   
 0.791
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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