Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05635.1PFAM: Biotin/lipoate A/B protein ligase; KEGG: hvo:HVO_1815 biotin/lipoate A/B protein ligase family domain-containing protein. (243 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.927
AEN06536.1
PFAM: Biotin/lipoate A/B protein ligase; KEGG: hvo:HVO_0572 lipoate protein ligase.
     
  0.900
AEN05634.1
KEGG: hla:Hlac_2125 hypothetical protein.
       0.855
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.831
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
     
 0.763
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
  
 0.755
AEN06483.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: hla:Hlac_0141 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
  
 0.657
AEN05165.1
KEGG: hvo:HVO_2334 hypothetical protein.
  
     0.463
AEN05633.1
KEGG: hbo:Hbor_03990 hypothetical protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily.
       0.455
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
   0.439
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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