STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN05647.1HhH-GPD family protein; KEGG: hma:rrnAC1088 DNA-3-methyladenine glycosylase; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. (217 aa)    
Predicted Functional Partners:
AEN05648.1
KEGG: hbo:Hbor_12310 metal-dependent hydrolase, beta-lactamase superfamily III.
  
    0.524
dbh
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
  
 
 0.516
nfo
Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
   
 
 0.512
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.504
AEN04767.1
ERCC4 domain protein; KEGG: hbo:Hbor_02260 ERCC4-like helicase; PFAM: ERCC4 domain; DNA/RNA helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helix-hairpin-helix DNA-binding motif, class 1.
    
   0.495
mutS-2
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
 0.442
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.435
AEN06886.1
Band 7 protein; KEGG: hbo:Hbor_24160 SPFH domain, band 7 family protein; PFAM: Band 7 protein; SMART: Band 7 protein.
  
    0.411
AEN06788.1
PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; KEGG: hbo:Hbor_24310 methylated DNA-protein cysteine methyltransferase.
 
  
 0.407
AEN05114.1
KEGG: hbo:Hbor_18650 acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA oxidase/dehydrogenase, central region; Acyl-CoA dehydrogenase, N-terminal.
  
  
 0.406
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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