Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (493 aa)    
Predicted Functional Partners:
AEN04586.1
KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
 
     0.946
AEN05690.1
PUA domain containing protein; KEGG: hbo:Hbor_06070 tRNA-archaeosine synthase; PFAM: Pseudouridine synthase/archaeosine transglycosylase; Queuine/other tRNA-ribosyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
 
 
0.901
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.777
AEN05693.1
PFAM: NUDIX hydrolase domain; KEGG: hwa:HQ3084A ADP-ribose pyrophosphatase; Mut/NUDIX family protein.
       0.771
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.648
AEN05692.1
PFAM: Abortive infection protein; KEGG: hma:rrnAC0355 hypothetical protein.
  
    0.646
AEN06344.1
Peptidase M50; KEGG: hwa:HQ1095A metalloprotease/metallo peptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF.
 
  
 0.595
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
 
    0.565
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.556
AEN06411.1
KEGG: hvo:HVO_1965 Nob1p-like protein.
  
    0.549
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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