Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
AEN05737.1PFAM: NUDIX hydrolase domain; KEGG: nmg:Nmag_1423 NUDIX hydrolase. (168 aa)    
Predicted Functional Partners:
AEN05738.1
KEGG: hvo:HVO_0791 methylated-DNA--protein-cysteinemethyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding.
     
 0.714
AEN06691.1
KEGG: hbo:Hbor_26920 L-threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
       0.698
rad25
Type III restriction protein res subunit; KEGG: hbo:Hbor_14720 DNA/RNA helicase, superfamily II; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
  
  
 0.548
AEN05739.1
Hypothetical protein.
       0.539
AEN04806.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hvo:HVO_1143 CDP-diacylglycerol-serine O phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.503
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
     
 0.503
secF
SecD/SecF/SecDF export membrane protein; Involved in protein export.
       0.480
secD
Preprotein translocase subunit SecD; Involved in protein export.
       0.478
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.461
AEN04737.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hbo:Hbor_01460 single-stranded DNA-specific exonuclease.
  
  
 0.429
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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