Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
secFSecD/SecF/SecDF export membrane protein; Involved in protein export. (289 aa)    
Predicted Functional Partners:
secD
Preprotein translocase subunit SecD; Involved in protein export.
 
 0.999
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.823
AEN05739.1
Hypothetical protein.
       0.672
AEN05738.1
KEGG: hvo:HVO_0791 methylated-DNA--protein-cysteinemethyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding.
 
     0.615
AEN04926.1
PFAM: Phosphoesterase, RecJ-like; Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hvo:HVO_1018 hypothetical protein.
 
     0.581
AEN05274.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA binding domain; KEGG: hla:Hlac_1616 nucleic acid binding OB-fold tRNA/helicase-type.
 
     0.553
eif1a
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
    0.544
atpE
V-type proton ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.528
AEN05862.1
PFAM: Protein of unknown function DUF112, transmembrane; KEGG: hla:Hlac_2339 protein of unknown function DUF112 transmembrane.
  
     0.523
AEN05737.1
PFAM: NUDIX hydrolase domain; KEGG: nmg:Nmag_1423 NUDIX hydrolase.
       0.480
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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