Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05760.1KEGG: hvo:HVO_2297 deoxyhypusine synthase; PFAM: Deoxyhypusine synthase. (354 aa)    
Predicted Functional Partners:
eif5a
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.982
AEN05761.1
KEGG: nmg:Nmag_2682 protein of unknown function DUF6 transmembrane.
  
    0.774
AEN05762.1
KEGG: hbo:Hbor_07120 hypothetical protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NGG1p interacting factor 3, NIF3.
   
   0.768
top6A
Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
     
 0.595
rpl6
Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.589
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
     
 0.581
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
   0.553
AEN04804.1
PFAM: PBS lyase HEAT-like repeat; KEGG: hbo:Hbor_21990 pbs lyase heat-like hypothetical protein.
  
 
 0.513
AEN06472.1
KEGG: hbo:Hbor_03090 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase alpha chain.
  
  
 0.493
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.475
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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