Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05767.1KEGG: hbo:Hbor_08360 glycine dehydrogenase (decarboxylating) alpha subunit; PFAM: Glycine cleavage system P-protein, N-terminal. (441 aa)    
Predicted Functional Partners:
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.999
AEN05768.1
PFAM: Glycine cleavage system P-protein, N-terminal; KEGG: hbo:Hbor_08350 glycine dehydrogenase (decarboxylating) subunit beta.
 0.999
AEN04662.1
TIGRFAM: Folate-binding, YgfZ; KEGG: hbo:Hbor_27940 aminomethyltransferase; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel.
 
 
 0.998
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.963
AEN06484.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hbo:Hbor_02940 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
  
 
 0.938
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.931
AEN06995.1
KEGG: hje:HacjB3_01035 threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase.
  
 
 0.923
AEN04949.1
KEGG: nmg:Nmag_0093 putative transcriptional regulator, GntR family; PFAM: Aminotransferase, class I/II.
   
 
  0.902
AEN05352.1
Serine--pyruvate transaminase; KEGG: htu:Htur_1862 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase.
    
 0.901
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.