Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05783.1PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: hsl:OE1719R oxidoreductase. (316 aa)    
Predicted Functional Partners:
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
  
 
 0.830
AEN04728.1
PFAM: Tetratricopeptide TPR-1; KEGG: hbo:Hbor_01120 tetratricopeptide hypothetical protein.
 
 0.563
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
  
 0.546
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
   
 0.531
AEN05780.1
PFAM: Alpha/beta hydrolase fold-1; KEGG: hvo:HVO_2702 putative hydrolase.
 
 0.522
AEN06557.1
Unspecific monooxygenase; KEGG: hbo:Hbor_01820 cytochrome P450; PFAM: Cytochrome P450.
 
 0.520
AEN05008.1
Unspecific monooxygenase; KEGG: hbo:Hbor_34020 cytochrome P450; PFAM: Cytochrome P450.
 
 0.519
AEN06715.1
KEGG: sti:Sthe_2364 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase.
  
  
 0.506
AEN06962.1
PFAM: Histone deacetylase superfamily; KEGG: hvo:HVO_0522 HdaI-type histone deacetylase.
   
 0.476
AEN06800.1
TIGRFAM: Glutamine synthetase type I; KEGG: hbo:Hbor_29510 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
  
 0.457
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]