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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEN05807.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (1433 aa)    
Predicted Functional Partners:
AEN06900.1
PFAM: Ribonucleotide reductase; KEGG: hje:HacjB3_00820 ribonucleotide-diphosphate reductase subunit beta.
 
 0.999
tmk
PFAM: Thymidylate kinase-like; TIGRFAM: Thymidylate kinase; HAMAP: Thymidylate kinase; KEGG: hvo:HVO_2207 thymidylate kinase.
  
 
 0.935
AEN07051.1
Transcriptional regulator, XRE family; KEGG: nph:NP5106A ATP-dependent DNA helicase (intein-containing); PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: DNA-dependent ATPase MCM; Hedgehog/intein hint, N-terminal; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; Belongs to the MCM family.
 
 
 0.932
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.921
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 0.918
AEN06899.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 
0.910
AEN07130.1
Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
   
 
  0.903
cmk
TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase; KEGG: hvo:HVO_2494 cytidylate kinase; PFAM: Adenylate kinase.
    
  0.902
AEN04827.1
Transcriptional activator, TenA family; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C; KEGG: hla:Hlac_2986 transcriptional activator, TenA family.
     
 0.863
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 
 0.820
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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