STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa)    
Predicted Functional Partners:
AEN05062.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hbo:Hbor_25070 aminodeoxychorismate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I, C-terminal.
 
 0.999
AEN05810.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hmu:Hmuk_1768 glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal.
 
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
trpF
KEGG: hla:Hlac_1940 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.
 
 
 0.999
AEN05063.1
TIGRFAM: Para-aminobenzoate synthase/anthranilate synthase, component I; KEGG: htu:Htur_1366 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
 
 0.998
trpC
KEGG: hbo:Hbor_24300 indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.998
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.994
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.993
AEN05387.1
PFAM: Cytochrome c oxidase, subunit I; Cytochrome c oxidase, subunit III; KEGG: hbo:Hbor_15740 heme/copper-type cytochrome/quinol oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.
     
 0.752
AEN06765.1
PFAM: Aminotransferase, class I/II; KEGG: hmu:Hmuk_0141 L-threonine-O-3-phosphate decarboxylase.
  
  
 0.662
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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